Gastrointestinal Autoimmunity

Sessions on gastrointestinal autoimmunity recommended by Prof. Aaron Lerner, Germany

A. Celiac disease: novelties in 2016

This session can offer the gastroenterologist:

1. updating on celiac disease pathophysiology and future therapies

2. New diagnostic serological bio-markers in celiac disease diagnosis and follow up: the neo-epitope and the microbial transglutaminase story.

3. Celiac disease autoantibodies: bystanders/functional or pathogenic?

Highlights: Dan Leffler, Torsten Matthias ​and Karina Lopez presentations

 Session Celiac disease - novelties in 2016.pdf

B. The autoimmune origin of celiac and gastrointestinal diseases

This session can offer the gastroenterologist:

1. The new area of fecal markers for GI and systemic autoimmunity

2. Serum autoantibodies reflections of gastrointestinal and remote organ autoimmunity

3. The place of the gut in organ specific autoimmunity

Highlights: Ettore Capoluongo, Marie Isabelle, Maximilian Hoffmann presentations​

Session The autoim​mune origin of celiac and gastrointestinal disease.pdf


Professor Aaron Lerner, MD, MHA.

B. Rappaport School of medicine, Technion-Israel Institute of technology, Haifa, Israel. After receiving his MD from the Sakler school of medicine, Tel-Aviv University (1976), Professor Lerner  specialized in Pediatrics ( 1982 ), Pediatric Gastroenterology and Nutrition (  1984 ) and Adult Gastroenterology ( 1987).  Took several senior positions as head of Department of pediatrics (1995-2005) and head of Pediatric Gastroenterology and Nutrition unit, at the Carmel Medical Center, Haifa, Israel. Finished his Medical Management degree  M.H.A, at Ben- Gurion University, Beer-Sheba, Israel (1999), spent research sabbaticals in Hahnemann University, Philadelphia, PA, USA (1991),  State University of North Carolina, Chapel Hill, N.C,U.S.A (2005) and currently, in an extended scientific sabbatical in Aesku.Kipp Institute, Wendelsheim, Germany.(2014-16). 

Main clinical interests: pediatric nutrition, nutritional assessment and deficiencies, celiac and Crohn's diseases, Mendelian and poly-genetic conditions and characterization of new genetic disease like glycogen storage disease XIc, Congenital alpha-glucosidase deficiency, New mutations in Cystic fibrosis, Peutz Jeger syndrome, ataxia telangiectasia .

Main research area: pathogenesis, diagnosis and treatment of systemic autoimmune diseases (ADs) in particular gastrointestinal conditions, environmental inducers of ADs, micro/dysbiosis and the place of post-translational modification of protein in ADs induction, new serological marker of celiac disease (anti endomysial in 1984, anti-neo-epitope tTg in 2011, anti-microbial and anti neo microbial transglutaminase in 2014-6), Industrial food processing additive that breach tight-junction integrity, the multi gut-remote organs' axes in systemic autoimmunity and the non-celiac side effects of gluten.

Prof. Lerner presented in numerous international congresses, mainly of pediatrics, nutrition and autoimmunity, published 250 manuscripts in peer reviewed journals and is on the editorial board of 14 international journal.

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